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How much does it cost to make Gleevec? Generic imatinib is sold at $8,800 /year in Canada 12 and at about $400/year in India. The cost to manufacture a 1-year supply of 400-mg imatinib tablets is $159. Two years from now, the price of generic imatinib in the United States (or purchased from abroad) will be significantly lower, hopefully less than $1,000/year.
What type of inhibitor is imatinib Gleevec? Imatinib (also called Gleevec or STI571) is a small-molecule inhibitor that binds to the kinase domain of BCR-ABL and stabilizes the protein in its closed, inactive conformation (5), thereby inhibiting its activity, and is now a first-line therapy for the majority of chronic myelogenous leukemia (CML) cases because of
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